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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2BP1
All Species:
40.91
Human Site:
T222
Identified Species:
100
UniProt:
Q9NZI8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZI8
NP_006537.3
577
63456
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Chimpanzee
Pan troglodytes
XP_511944
577
63448
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Rhesus Macaque
Macaca mulatta
XP_001091611
577
63469
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Dog
Lupus familis
XP_548184
577
63447
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Cat
Felis silvestris
Mouse
Mus musculus
O88477
577
63432
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Rat
Rattus norvegicus
Q8CGX0
577
63418
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512362
584
64248
T223
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Chicken
Gallus gallus
O42254
576
63253
T222
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Frog
Xenopus laevis
O57526
593
65367
T231
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Zebra Danio
Brachydanio rerio
Q08CK7
598
65511
T225
G
A
T
I
R
N
I
T
K
Q
T
Q
S
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
99.8
N.A.
99.3
99.6
N.A.
76.8
94.4
76.2
78.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.8
99.8
N.A.
99.4
99.8
N.A.
87.1
96.8
86.8
86.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
100
0
0
0
0
0
0
0
100
% I
% Lys:
0
0
0
0
0
0
0
0
100
0
0
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
100
0
100
0
0
0
% Q
% Arg:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% S
% Thr:
0
0
100
0
0
0
0
100
0
0
100
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _